Monday, July 10
8:45 - 9:00 Welcome
9:00 - 10:00 Prof. Michael Levitt - Introducing molecular forces.
10:00 - 11:00 Prof. Michael Levitt - Simulation of protein and nucleic
acid dynamics
11:00 - 11:20 Coffee Break
11:20 - 12:20 Prof. Ken Dill - Protein stability, aggregation, and mean-field
models
12:20 - 13:20 Prof. Ken Dill - Water and the hydrophobic effect
13:30 Lunch
15:00 - 19:00 Homework and Seminar Sessions
20:00 Dinner
Tuesday, July 11
8:45 - 9:00 Welcome
9:00 - 10:00 Prof. John Moult - Comparative Modeling
10:00 - 11:00 Prof. Ken Dill - New Computational methods for conformational
searching
11:00 - 11:20 Coffee Break
11:20 - 12:20 Prof. Michael Levitt - Predicting protein structure
12:20 - 13:20 Prof. Michael Levitt - Bio-informatics and structural genomics
13:30 Lunch
15:00 - 16:00 Prof. Ken Dill - New Computational methods for conformational
searching
16:00 - 17:00 Prof. Ken Dill - Graph-theoretic methods for conformational
transitions
20:00 Dinner
Wednesday, July 12
9:00 - 10:00 Prof. Arthur Lesk - Sequence-structure relationships in proteins.
10:00 - 11:00 Prof. Arthur Lesk - Genomics and proteomics
11:00 - 11:20 Coffee Break
11:20 - 12:20 Prof. Haim Wolfson - Computer Vision Motivated Algorithms for
Structural Motif Detection in Proteins.
12:20 - 13:20 Prof. Haim Wolfson - Structural Alignment of Flexible Molecules.
13:30 Lunch
20:00 Dinner
Thursday, July 13
9:00 - 10:00 Prof. Ken Dill - Graph-theoretic methods for conformational
transitions
10:00 - 11:00 Prof. John Moult - Fold recognition
11:00 - 11:20 Coffee Break
11:20 - 12:20 Prof. Arthur Lesk - Analysis, comparison and classification of
protein structures
12:20 - 13:20 Prof. Arthur Lesk - Protein evolution. Conformational change in proteins
13:30 Lunch
15:00 - 17:00 Homework and Seminar Sessions
20:00 Dinner
Friday, July 14
9:00 - 10:00 Prof. John Moult - Ab initio prediction
10:00 - 11:00 Prof. John Moult - Discriminatory functions.
11:00 - 11:20 Coffee Break
11:20 - 12:20 Prof. Haim Wolfson - Molecular Surface Representation and
Critical Feature Extraction.
12:20 - 13:20 Prof. Haim Wolfson - Geometric Docking Methods.
13:30 Lunch
15:00 - 17:00 Homework and Seminar Sessions
20:00 Dinner
Workshop on Protein Structure
Martina Franca, Italy, July 15
Invited Speakers and timetable
Check for last minute news about the workshop
9:00 - 10:00 Invited Lecture
Mary Ellen Bock (USA)
Some Statistical Problems in Biotechnology
10:00 - 12:30
1 J. R. Quine (USA)
Protein Structures from solid state NMR: Mathematical
and Technical Challenges
2 A. Rossi, C. Micheletti, F. Seno and A. Maritan (Italy)
Knolwedge-based self-consistent scheme to design proteins
with a reduced number of amino acis classes.
3 Claus Lundegaard, Thomas Nordahl Petersen, Morten Nielsen, Henrik Bohr,
Jakob Bohr, Soren Brunak, Garry P. Gippert and Ole Lund (Denmark)
Prediction of protein secondary structure at high accuracy
using a combination of many neural networks
4 Rolf Backofen (Germany)
An Upper Bound for Number of Contacts in the HP-Model on the
Face-Centered-Cubic Lattice (FCC): Applications and Results.
5 Vasily Ramensky, Shamil Sunyaev and Peer Bork (Russia/Germany)
Mapping non-synonymous single nucleotide polymorphisms onto
proteins: from human genome variation to protein structure
12:30 Lunch
2:30 - 3:30 Invited Lecture
Andrea Califano (USA)
Functional and Structural Genomics: moving from analysis to
synthesis in the biological sciences
3:30 - 6:00
6 Maricel Kann and Richard Goldstein (USA)
Optimizing for success: a new score function for distantly
related protein sequence comparison.
7 Dean C. Adams and Gavin J. P. Naylor (USA)
Assessing the structural similarity of proteins: a comparison
of existing methods and geometric morphometric tecniques
8 H.-O Bertrand, A.-S. Bessis, T. Galvez, J.P. Pin and F. Acher (France)
Metabotropic glutamate receptor binding domain. A homology
modeling study
9 Yves-Henri Sanejouand (France)
10 N. Kannan and S. Visheverhwara (India)
A graph spectral algorithm to identify conserved features among
topologically similar proteins
11 F.Seno, C. Micheletti, J.R. Banavar and A. Maritan (Italy)
An optimal procedure to learn effective amino acid interaction
potentials.
Mary Ellen Bock, Purdue University, USA
Andrea Califano, IBM Yorktown, USA
IMPORTANT DATES
Deadline for submission of abstracts to the workshop: March 15, 2000
Notification of acceptance: April 15, 2000
Electronic submission is encouraged.
For an electronic submission, please attach your manuscript to an email and
send it to either
guerra@dei.unipd.it or to scistra@frodo2.cs.sandia.gov in
one of the following formats:
Postscript, PDF, or Microsoft Word.
Alternatively, two copies of an extended abstract (preferably
two sided copies) can be submitted via regular mail to:
SORIN ISTRAIL
Sandia National Laboratories
P.O. Box 5800, Mail Stop 1110
Albuquerque, NM 87185-1110
(505) 845-7612
The extended abstract must not exceed 12 pages (using 11 point or
larger font, with not less than one inch margins all around), including the
bibliography and the figures.
This C.I.M.E. course is made possible thanks to the generous support
received from:
The European Commission, Division XII, TMR Programme "Summer Schools"
Consiglio Nazionale delle Ricerche
Ministero dell' Universita' e della Ricerca Scientifica e Tecnologica
UNESCO-ROSTE, Venice Office.
